ea0014s11.1 | Polycystic ovary syndrome | ECE2007
Schuering Andreas
, Jurgens Andrea
, Gromoll Jorg
, Zitzmann Michael
, Sonntag Barbara
, Nieschlag Eberhard
, Greb Robert
, Kiesel Ludwig
Introduction: Polycystic ovary syndrome (PCOS) is a frequent disorder with a variable phenotype and a suspected genetic background. Androgenic effects constitute the central mechanism for the clinical, biochemical and sonographic features of PCOS. Androgenic effects are transported by the androgen receptor, whose activity can be modulated by a genetic polymorphism. We investigated the role of the CAG repeat polymorphism of the androgen receptor in PCOS.P...